Official symbol | NUP153 |
Gene id | 9972 |
Organism | Homo sapiens |
Official full symbol | nucleoporin 153 |
Gene type | protein-coding |
Also known as | HNUP153, N153 |
Summary | Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. |
Genomic regions | Chromosome 6 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
NUP153-202 | ENST00000537253.5 | 6030 | 1506aa | Protein coding | CCDS64359 | P49790-3 | - | TSL:2, GENCODE basic, APPRIS ALT2, |
NUP153-201 | ENST00000262077.3 | 6026 | 1475aa | Protein coding | CCDS4541 | P49790-1 | NM_005124.4 | TSL:1, GENCODE basic, APPRIS P2, MANE Select v0.92, |
NUP153-203 | ENST00000613258.4 | 5811 | 1433aa | Protein coding | CCDS75407 | P49790-2 | - | TSL:1, GENCODE basic, |
Target Gene | NUP153 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene NUP153 had been KO in hela cell line. |
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