CRISPR-U™ Gene Knockout Cell Line Strategy

GLP2R Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human GLP2R Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol GLP2R
Gene id 9340
Organism Homo sapiens
Official full symbol glucagon like peptide 2 receptor
Gene type protein-coding
Summary This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.
Genomic regions Chromosome 17
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
GLP2R-201 ENST00000262441.10 4196 553aa Protein coding CCDS11150 A0A384MTS7 O95838 NM_004246.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
GLP2R-204 ENST00000574745.5 1882 373aa Protein coding - I3L0P5 - TSL:2, GENCODE basic,
GLP2R-202 ENST00000304773.5 523 118aa Protein coding - E9PC86 - CDS 3' incomplete, TSL:2,
GLP2R-203 ENST00000458005.2 2606 93aa Nonsense mediated decay - H0Y6C2 - TSL:5,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene GLP2R
This KO Strategy loading
Red Cotton™ Notes Gene GLP2R had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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