CRISPR-U™ Gene Knockout Cell Line Strategy

BAZ1B Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human BAZ1B Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol BAZ1B
Gene id 9031
Organism Homo sapiens
Official full symbol bromodomain adjacent to zinc finger domain 1B
Gene type protein-coding
Also known as WBSCR10, WBSCR9, WSTF
Summary This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
Genomic regions Chromosome 7
Strategy Summary
This gene has 2 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
BAZ1B-201 ENST00000339594.9 6115 1483aa Protein coding CCDS5549 Q9UIG0-1 NM_032408.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
BAZ1B-202 ENST00000404251.1 5428 1483aa Protein coding CCDS5549 Q9UIG0-1 - TSL:2, GENCODE basic, APPRIS P1,
BAZ1B-203 ENST00000466844.1 827 No protein Retained intron - - - TSL:4,
Ubigene Red Cotton Transcript
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Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene BAZ1B
This KO Strategy loading
Red Cotton™ Notes Gene BAZ1B had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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