CRISPR-U™ Gene Knockout Cell Line Strategy

MPZL1 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human MPZL1 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol MPZL1
Gene id 9019
Organism Homo sapiens
Official full symbol myelin protein zero like 1
Gene type protein-coding
Also known as MPZL1b, PZR, PZR1b, PZRa, PZRb
Genomic regions Chromosome 1
Strategy Summary
This gene has 4 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
MPZL1-201 ENST00000359523.7 4978 269aa Protein coding CCDS1264 O95297-1 NM_003953.6 TSL:1, GENCODE basic, APPRIS P3, MANE Select v0.92,
MPZL1-203 ENST00000392121.7 3421 119aa Protein coding CCDS53425 O95297-5 - TSL:2, GENCODE basic,
MPZL1-209 ENST00000474859.5 630 209aa Protein coding CCDS44273 O95297-3 - TSL:1, GENCODE basic, APPRIS ALT1,
MPZL1-202 ENST00000367853.3 881 183aa Protein coding - Q9UEL6 - CDS 5' incomplete, TSL:1,
MPZL1-205 ENST00000448405.5 1596 95aa Nonsense mediated decay - F8WFC4 - TSL:1,
MPZL1-204 ENST00000403379.3 961 No protein Processed transcript - - - TSL:5,
MPZL1-211 ENST00000498279.1 534 No protein Processed transcript - - - TSL:4,
MPZL1-210 ENST00000487858.1 420 No protein Processed transcript - - - TSL:4,
MPZL1-208 ENST00000474729.5 1335 No protein Retained intron - - - TSL:1,
MPZL1-207 ENST00000465787.5 1305 No protein Retained intron - - - TSL:1,
MPZL1-206 ENST00000464954.1 607 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene MPZL1
This KO Strategy loading
Red Cotton™ Notes Gene MPZL1 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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