CRISPR-U™ Gene Knockout Cell Line Strategy

SELENBP1 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human SELENBP1 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol SELENBP1
Gene id 8991
Organism Homo sapiens
Official full symbol selenium binding protein 1
Gene type protein-coding
Also known as EHMTO, HEL-S-134P, LPSB, MTO, SBP56, SP56, hSBP
Summary This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Genomic regions Chromosome 1
Strategy Summary
This gene has 6 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
SELENBP1-204 ENST00000426705.6 1928 514aa Protein coding CCDS60266 Q13228-4 - TSL:2, GENCODE basic,
SELENBP1-201 ENST00000368868.10 1722 472aa Protein coding CCDS995 Q13228-1 NM_003944.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
SELENBP1-208 ENST00000447402.7 1530 410aa Protein coding CCDS58027 Q13228-3 - TSL:2, GENCODE basic,
SELENBP1-211 ENST00000458566.5 929 295aa Protein coding - A6PVX1 - CDS 3' incomplete, TSL:5,
SELENBP1-203 ENST00000424475.5 916 305aa Protein coding - H0Y532 - CDS 5' and 3' incomplete, TSL:5,
SELENBP1-205 ENST00000427867.2 377 80aa Protein coding - C9JVL0 - CDS 3' incomplete, TSL:5,
SELENBP1-202 ENST00000423070.5 1887 165aa Nonsense mediated decay - F8WCR4 - TSL:5,
SELENBP1-207 ENST00000443708.5 1724 123aa Nonsense mediated decay - F2Z2W8 - TSL:5,
SELENBP1-206 ENST00000427977.6 1611 123aa Nonsense mediated decay - F2Z2W8 - TSL:5,
SELENBP1-209 ENST00000455397.5 1521 123aa Nonsense mediated decay - F2Z2W8 - TSL:5,
SELENBP1-210 ENST00000455839.5 788 47aa Nonsense mediated decay - F8WBA9 - TSL:5,
SELENBP1-215 ENST00000473693.5 722 No protein Processed transcript - - - TSL:5,
SELENBP1-219 ENST00000498494.1 652 No protein Processed transcript - - - TSL:3,
SELENBP1-216 ENST00000474352.5 2840 No protein Retained intron - - - TSL:2,
SELENBP1-214 ENST00000470345.5 2128 No protein Retained intron - - - TSL:2,
SELENBP1-218 ENST00000493560.5 1963 No protein Retained intron - - - TSL:5,
SELENBP1-212 ENST00000463664.5 1922 No protein Retained intron - - - TSL:5,
SELENBP1-217 ENST00000492643.5 933 No protein Retained intron - - - TSL:3,
SELENBP1-213 ENST00000465273.1 342 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene SELENBP1
This KO Strategy loading
Red Cotton™ Notes Gene SELENBP1 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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