CRISPR-U™ Gene Knockout Cell Line Strategy

MPND Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human MPND Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol MPND
Gene id 84954
Organism Homo sapiens
Official full symbol MPN domain containing
Gene type protein-coding
Genomic regions Chromosome 19
Strategy Summary
This gene has 7 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
MPND-207 ENST00000599840.6 1614 501aa Protein coding CCDS74261 W4VSR2 NM_001300862.2 TSL:5, GENCODE basic, APPRIS P2, MANE Select v0.92,
MPND-201 ENST00000262966.12 1567 471aa Protein coding CCDS42470 Q8N594-1 - TSL:1, GENCODE basic, APPRIS ALT2,
MPND-202 ENST00000359935.8 1475 451aa Protein coding CCDS54200 Q8N594-2 - TSL:2, GENCODE basic,
MPND-205 ENST00000596722.5 1578 503aa Protein coding - M0R189 - CDS 5' incomplete, TSL:2,
MPND-206 ENST00000597036.5 1445 469aa Protein coding - M0R0F2 - CDS 5' incomplete, TSL:5,
MPND-203 ENST00000594162.1 407 109aa Protein coding - M0QXC4 - CDS 5' incomplete, TSL:3,
MPND-208 ENST00000601877.1 379 121aa Protein coding - M0QXK5 - CDS 5' incomplete, TSL:5,
MPND-204 ENST00000594716.5 1547 419aa Nonsense mediated decay - M0R044 - TSL:1,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene MPND
This KO Strategy loading
Red Cotton™ Notes Gene MPND had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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