CRISPR-U™ Gene Knockout Cell Line Strategy

NTPCR Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human NTPCR Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol NTPCR
Gene id 84284
Organism Homo sapiens
Official full symbol nucleoside-triphosphatase, cancer-related
Gene type protein-coding
Also known as C1orf57, HCR-NTPase, THEP1
Summary The protein encoded by this gene is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This gene is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. However, the cytotoxicity is not related to its triphosphatase activity.
Genomic regions Chromosome 1
Strategy Summary
This gene has 2 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
NTPCR-202 ENST00000366628.10 6324 190aa Protein coding CCDS1597 Q5TDE9 Q9BSD7 NM_032324.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
NTPCR-201 ENST00000366627.4 1762 228aa Protein coding - Q5TDF0 - TSL:3, GENCODE basic,
NTPCR-205 ENST00000490098.1 8705 No protein Processed transcript - - - TSL:1,
NTPCR-206 ENST00000490807.5 980 No protein Processed transcript - - - TSL:2,
NTPCR-208 ENST00000496662.5 882 No protein Processed transcript - - - TSL:2,
NTPCR-207 ENST00000494689.5 767 No protein Processed transcript - - - TSL:2,
NTPCR-203 ENST00000479125.5 761 No protein Processed transcript - - - TSL:3,
NTPCR-204 ENST00000487953.1 527 No protein Processed transcript - - - TSL:3,
Ubigene Red Cotton Transcript
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Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene NTPCR
This KO Strategy loading
Red Cotton™ Notes Gene NTPCR had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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