Official symbol | MAF1 |
Gene id | 84232 |
Organism | Homo sapiens |
Official full symbol | MAF1 homolog, negative regulator of RNA polymerase III |
Gene type | protein-coding |
Summary | This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. |
Genomic regions | Chromosome 8 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
MAF1-201 | ENST00000322428.10 | 1715 | 256aa | Protein coding | CCDS6416 | Q9H063 | NM_032272.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
MAF1-204 | ENST00000532522.5 | 1098 | 256aa | Protein coding | CCDS6416 | Q9H063 | - | TSL:5, GENCODE basic, APPRIS P1, |
MAF1-205 | ENST00000534585.5 | 1754 | 286aa | Protein coding | - | E9PSH4 | - | TSL:5, GENCODE basic, |
MAF1-202 | ENST00000527058.1 | 868 | 252aa | Protein coding | - | E9PR76 | - | CDS 3' incomplete, TSL:3, |
MAF1-203 | ENST00000527572.5 | 737 | 70aa | Protein coding | - | E9PJ05 | - | CDS 3' incomplete, TSL:3, |
MAF1-206 | ENST00000534811.1 | 632 | 164aa | Protein coding | - | H0YEV4 | - | CDS 5' incomplete, TSL:2, |
Target Gene | MAF1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene MAF1 had been KO in hek293t cell line. |
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