CRISPR-U™ Gene Knockout Cell Line Strategy

MEX3B Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human MEX3B Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol MEX3B
Gene id 84206
Organism Homo sapiens
Official full symbol mex-3 RNA binding family member B
Gene type protein-coding
Also known as MEX-3B, RKHD3, RNF195
Summary This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies.
Genomic regions Chromosome 15
Strategy Summary
This gene has 2 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
MEX3B-201 ENST00000329713.5 3405 569aa Protein coding CCDS10319 Q6ZN04-1 NM_032246.6 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
MEX3B-202 ENST00000558133.1 4333 158aa Protein coding - Q6ZN04-3 - TSL:NA, GENCODE basic,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene MEX3B
This KO Strategy loading
Red Cotton™ Notes Gene MEX3B had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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