Official symbol | KDM5C |
Gene id | 8242 |
Organism | Homo sapiens |
Official full symbol | lysine demethylase 5C |
Gene type | protein-coding |
Also known as | DXS1272E, JARID1C, MRX13, MRXJ, MRXSCJ, MRXSJ, SMCX, XE169 |
Summary | This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. |
Genomic regions | Chromosome X |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
KDM5C-208 | ENST00000452825.7 | 6096 | 1379aa | Protein coding | CCDS55417 | P41229-4 | - | TSL:5, GENCODE basic, |
KDM5C-204 | ENST00000375401.8 | 5810 | 1560aa | Protein coding | CCDS14351 | P41229-1 | NM_004187.5 | TSL:1, GENCODE basic, APPRIS P4, MANE Select v0.92, |
KDM5C-205 | ENST00000404049.7 | 5677 | 1559aa | Protein coding | CCDS65269 | P41229-5 | - | TSL:1, GENCODE basic, APPRIS ALT2, |
KDM5C-202 | ENST00000375379.7 | 5245 | 1557aa | Protein coding | CCDS87747 | P41229-2 | - | TSL:5, GENCODE basic, APPRIS ALT2, |
KDM5C-203 | ENST00000375383.7 | 5122 | 1516aa | Protein coding | - | P41229-3 | - | TSL:5, GENCODE basic, |
KDM5C-207 | ENST00000429877.5 | 870 | 53aa | Nonsense mediated decay | - | F8WDK1 | - | TSL:3, |
KDM5C-206 | ENST00000428012.1 | 766 | 99aa | Nonsense mediated decay | - | F8WF56 | - | TSL:3, |
KDM5C-201 | ENST00000349663.6 | 548 | 74aa | Nonsense mediated decay | - | F8W7H7 | - | TSL:4, |
KDM5C-209 | ENST00000465402.1 | 720 | No protein | Processed transcript | - | - | - | TSL:3, |
KDM5C-213 | ENST00000495519.1 | 600 | No protein | Processed transcript | - | - | - | TSL:3, |
KDM5C-210 | ENST00000467093.1 | 446 | No protein | Processed transcript | - | - | - | TSL:3, |
KDM5C-211 | ENST00000477109.1 | 297 | No protein | Processed transcript | - | - | - | TSL:3, |
KDM5C-214 | ENST00000497100.5 | 1403 | No protein | Retained intron | - | - | - | TSL:5, |
KDM5C-212 | ENST00000481369.1 | 1361 | No protein | Retained intron | - | - | - | TSL:2, |
KDM5C-215 | ENST00000497995.1 | 394 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | KDM5C |
This KO Strategy | loading |
Red Cotton™ Notes | Gene KDM5C had been KO in hek293t cell line. |
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