CRISPR-U™ Gene Knockout Cell Line
Strategy
APOL6 Gene Knockout Strategy
CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general
CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has
successfully edited over 3000 genes on more than 100 types of cell lines.
Objective
To create a Human APOL6 Knockout
model in cell line by
CRISPR-U™-mediated
genome
engineering.
Target gene info 
| Official symbol | APOL6 |
| Gene id | 80830 |
| Organism | Homo sapiens |
| Official full symbol | apolipoprotein L6 |
| Gene type | protein-coding |
| Also known as | APOL-VI, APOLVI |
| Summary | This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. |
| Genomic regions | Chromosome 22 |
Strategy Summary
This gene has 1 protein coding transcripts：
| Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
| APOL6-201 | ENST00000409652.5 | 10065 | 343aa | Protein coding | CCDS13919 | B3KTP4 Q9BWW8 | NM_030641.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
Strategy
Click to get
Red Cotton™ Assessment
Project Difficulty Level unknown
| Target Gene | APOL6 |
| This KO Strategy | loading |
| Red Cotton™ Notes | Gene APOL6 had been KO in a549 cell line. |
Aforementioned information comes from Ubigene database. Different origin of cell lines may have
different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Work flow
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