CRISPR-U™ Gene Knockout Cell Line Strategy

DYNLT3 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human DYNLT3 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol DYNLT3
Gene id 6990
Organism Homo sapiens
Official full symbol dynein light chain Tctex-type 3
Gene type protein-coding
Also known as RP3, TCTE1L, TCTEX1L
Summary This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.
Genomic regions Chromosome X
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
DYNLT3-201 ENST00000378578.9 2151 116aa Protein coding CCDS14243 P51808 NM_006520.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
DYNLT3-202 ENST00000378581.7 920 152aa Protein coding - A6NGJ0 - TSL:2, GENCODE basic,
DYNLT3-203 ENST00000432389.2 719 122aa Protein coding - F2Z328 - TSL:5, GENCODE basic,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene DYNLT3
This KO Strategy loading
Red Cotton™ Notes Gene DYNLT3 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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