CRISPR-U™ Gene Knockout Cell Line Strategy

SNCG Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human SNCG Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol SNCG
Gene id 6623
Organism Homo sapiens
Official full symbol synuclein gamma
Gene type protein-coding
Also known as BCSG1, SR
Summary This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development.
Genomic regions Chromosome 10
Strategy Summary
This gene has 2 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
SNCG-202 ENST00000372017.4 756 127aa Protein coding CCDS7380 O76070 Q6FHG5 NM_003087.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
SNCG-201 ENST00000348795.8 684 126aa Protein coding CCDS81483 F8W754 - TSL:2, GENCODE basic,
SNCG-204 ENST00000483064.1 794 No protein Processed transcript - - - TSL:2,
SNCG-203 ENST00000465679.5 641 No protein Processed transcript - - - TSL:2,
Ubigene Red Cotton Transcript
Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene SNCG
This KO Strategy loading
Red Cotton™ Notes Gene SNCG had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

Please leave your suggestion ×