CRISPR-U™ Gene Knockout Cell Line Strategy

IPPK Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human IPPK Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol IPPK
Gene id 64768
Organism Homo sapiens
Official full symbol inositol-pentakisphosphate 2-kinase
Gene type protein-coding
Also known as C9orf12, INSP5K2, IP5K, IPK1, bA476B13.1
Summary The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export.
Genomic regions Chromosome 9
Strategy Summary
This gene has 2 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
IPPK-201 ENST00000287996.8 4268 491aa Protein coding CCDS6699 Q9H8X2 NM_022755.6 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
IPPK-202 ENST00000375522.1 882 163aa Protein coding - X6R9A6 - TSL:3, GENCODE basic,
IPPK-203 ENST00000486841.1 2347 No protein Processed transcript - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene IPPK
This KO Strategy loading
Red Cotton™ Notes Gene IPPK had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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