CRISPR-U™ Gene Knockout Cell Line Strategy

CREB3L2 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human CREB3L2 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol CREB3L2
Gene id 64764
Organism Homo sapiens
Official full symbol cAMP responsive element binding protein 3 like 2
Gene type protein-coding
Also known as BBF2H7
Summary This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene.
Genomic regions Chromosome 7
Strategy Summary
This gene has 7 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
CREB3L2-201 ENST00000330387.11 7441 520aa Protein coding CCDS34760 Q70SY1-1 NM_194071.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
CREB3L2-203 ENST00000452463.5 1105 248aa Protein coding CCDS59083 Q70SY1-3 - TSL:1, GENCODE basic,
CREB3L2-207 ENST00000616381.4 7133 150aa Protein coding - A0A087WU77 - TSL:5, GENCODE basic,
CREB3L2-204 ENST00000456390.5 2360 460aa Protein coding - Q70SY1-2 - TSL:2, GENCODE basic,
CREB3L2-208 ENST00000620715.4 1053 175aa Protein coding - A0A087WUP1 - TSL:5, GENCODE basic,
CREB3L2-205 ENST00000458726.5 776 185aa Protein coding - C9JPH0 - TSL:3, GENCODE basic,
CREB3L2-202 ENST00000420629.1 719 239aa Protein coding - H7C1W8 - CDS 5' and 3' incomplete, TSL:3,
CREB3L2-206 ENST00000468127.1 596 No protein Processed transcript - - - TSL:3,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene CREB3L2
This KO Strategy loading
Red Cotton™ Notes Gene CREB3L2 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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