Official symbol | INF2 |
Gene id | 64423 |
Organism | Homo sapiens |
Official full symbol | inverted formin 2 |
Gene type | protein-coding |
Also known as | C14orf151, C14orf173, CMTDIE, FSGS5, pp9484 |
Summary | This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5. |
Genomic regions | Chromosome 14 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
INF2-203 | ENST00000392634.9 | 7623 | 1249aa | Protein coding | CCDS9989 | Q27J81-1 | NM_022489.4 | TSL:5, GENCODE basic, APPRIS P4, MANE Select v0.92, |
INF2-202 | ENST00000330634.11 | 7578 | 1240aa | Protein coding | CCDS45173 | Q27J81-2 | - | TSL:5, GENCODE basic, APPRIS ALT2, |
INF2-204 | ENST00000398337.8 | 1689 | 234aa | Protein coding | CCDS41999 | Q27J81-3 | - | TSL:1, GENCODE basic, |
INF2-227 | ENST00000675207.1 | 7732 | 1281aa | Protein coding | - | - | - | GENCODE basic, APPRIS ALT2, |
INF2-238 | ENST00000675638.1 | 7411 | 1222aa | Protein coding | - | - | - | GENCODE basic, APPRIS ALT2, |
INF2-245 | ENST00000675980.1 | 3768 | 1255aa | Protein coding | - | - | - | GENCODE basic, APPRIS ALT2, |
INF2-232 | ENST00000675481.1 | 3754 | 1250aa | Protein coding | - | - | - | GENCODE basic, APPRIS ALT2, |
INF2-230 | ENST00000675329.1 | 3726 | 1241aa | Protein coding | - | - | - | GENCODE basic, |
INF2-224 | ENST00000674991.1 | 2944 | 981aa | Protein coding | - | - | - | CDS 3' incomplete, |
INF2-213 | ENST00000674631.1 | 2200 | 614aa | Protein coding | - | - | - | CDS 5' incomplete, |
INF2-233 | ENST00000675482.1 | 1020 | 130aa | Protein coding | - | - | - | CDS 3' incomplete, |
INF2-216 | ENST00000674723.1 | 931 | 130aa | Protein coding | - | - | - | CDS 3' incomplete, |
INF2-250 | ENST00000676427.1 | 883 | 130aa | Protein coding | - | - | - | CDS 3' incomplete, |
INF2-221 | ENST00000674869.1 | 837 | 130aa | Protein coding | - | - | - | CDS 3' incomplete, |
INF2-212 | ENST00000674602.1 | 806 | 269aa | Protein coding | - | - | - | CDS 5' and 3' incomplete, |
INF2-210 | ENST00000617571.5 | 4556 | 1048aa | Nonsense mediated decay | - | Q8WYS3 | - | TSL:1, |
INF2-217 | ENST00000674757.1 | 3756 | 1051aa | Nonsense mediated decay | - | - | - | - |
INF2-214 | ENST00000674662.1 | 3755 | 776aa | Nonsense mediated decay | - | - | - | - |
INF2-243 | ENST00000675809.1 | 3749 | 793aa | Nonsense mediated decay | - | - | - | - |
INF2-211 | ENST00000674520.1 | 3689 | 878aa | Nonsense mediated decay | - | - | - | - |
INF2-219 | ENST00000674846.1 | 3689 | 773aa | Nonsense mediated decay | - | - | - | - |
INF2-220 | ENST00000674857.1 | 3683 | 194aa | Nonsense mediated decay | - | - | - | - |
INF2-244 | ENST00000675930.1 | 3639 | 1160aa | Nonsense mediated decay | - | - | - | - |
INF2-239 | ENST00000675724.1 | 3632 | 646aa | Nonsense mediated decay | - | - | - | - |
INF2-235 | ENST00000675583.1 | 3623 | 751aa | Nonsense mediated decay | - | - | - | - |
INF2-246 | ENST00000676016.1 | 3593 | 741aa | Nonsense mediated decay | - | - | - | - |
INF2-218 | ENST00000674822.1 | 3578 | 159aa | Nonsense mediated decay | - | - | - | - |
INF2-249 | ENST00000676366.1 | 3558 | 1133aa | Nonsense mediated decay | - | - | - | - |
INF2-222 | ENST00000674960.1 | 3552 | 316aa | Nonsense mediated decay | - | - | - | - |
INF2-242 | ENST00000675797.1 | 3099 | 358aa | Nonsense mediated decay | - | - | - | - |
INF2-201 | ENST00000252527.8 | 3050 | 717aa | Nonsense mediated decay | - | A0A0A0MQU1 | - | CDS 5' incomplete, TSL:2, |
INF2-225 | ENST00000674994.1 | 3006 | 230aa | Nonsense mediated decay | - | - | - | - |
INF2-241 | ENST00000675771.1 | 2957 | 332aa | Nonsense mediated decay | - | - | - | - |
INF2-231 | ENST00000675424.1 | 1051 | 18aa | Nonsense mediated decay | - | - | - | CDS 5' incomplete, |
INF2-215 | ENST00000674686.1 | 967 | 18aa | Nonsense mediated decay | - | - | - | CDS 5' incomplete, |
INF2-209 | ENST00000540171.2 | 1307 | No protein | Processed transcript | - | - | - | TSL:1, |
INF2-208 | ENST00000481338.1 | 1102 | No protein | Processed transcript | - | - | - | TSL:2, |
INF2-236 | ENST00000675603.1 | 934 | No protein | Processed transcript | - | - | - | - |
INF2-223 | ENST00000674966.1 | 859 | No protein | Processed transcript | - | - | - | - |
INF2-240 | ENST00000675743.1 | 648 | No protein | Processed transcript | - | - | - | - |
INF2-228 | ENST00000675248.1 | 577 | No protein | Processed transcript | - | - | - | - |
INF2-247 | ENST00000676100.1 | 528 | No protein | Processed transcript | - | - | - | - |
INF2-229 | ENST00000675313.1 | 432 | No protein | Processed transcript | - | - | - | - |
INF2-237 | ENST00000675616.1 | 431 | No protein | Processed transcript | - | - | - | - |
INF2-248 | ENST00000676134.1 | 382 | No protein | Processed transcript | - | - | - | - |
INF2-226 | ENST00000675029.1 | 1692 | No protein | Retained intron | - | - | - | - |
INF2-205 | ENST00000474229.1 | 947 | No protein | Retained intron | - | - | - | TSL:3, |
INF2-207 | ENST00000480763.2 | 581 | No protein | Retained intron | - | - | - | TSL:3, |
INF2-234 | ENST00000675557.1 | 547 | No protein | Retained intron | - | - | - | - |
INF2-206 | ENST00000477497.1 | 545 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | INF2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene INF2 had been KO in hela cell line. |
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