CRISPR-U™ Gene Knockout Cell Line Strategy

BLVRA Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human BLVRA Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol BLVRA
Gene id 644
Organism Homo sapiens
Official full symbol biliverdin reductase A
Gene type protein-coding
Also known as BLVR, BVR, BVRA
Summary The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene.
Genomic regions Chromosome 7
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
BLVRA-202 ENST00000402924.5 1161 296aa Protein coding CCDS5472 A0A140VJF4 P53004 - TSL:2, GENCODE basic, APPRIS P1,
BLVRA-201 ENST00000265523.9 1074 296aa Protein coding CCDS5472 A0A140VJF4 P53004 NM_000712.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
BLVRA-203 ENST00000424330.1 443 102aa Protein coding - C9J1E1 - CDS 3' incomplete, TSL:3,
BLVRA-204 ENST00000453612.1 757 No protein Retained intron - - - TSL:2,
BLVRA-205 ENST00000486984.1 324 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene BLVRA
This KO Strategy loading
Red Cotton™ Notes Gene BLVRA had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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