CRISPR-U™ Gene Knockout Cell Line Strategy

C19orf33 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human C19orf33 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol C19orf33
Gene id 64073
Organism Homo sapiens
Official full symbol chromosome 19 open reading frame 33
Gene type protein-coding
Also known as H2RSP, IMUP, IMUP-1, IMUP-2
Summary The protein encoded by this gene has been shown to be upregulated in SV40-immortalized fibroblasts as well as in endometrial carcinoma cells. The encoded protein is found primarily in the nucleus. This protein may play a role in placental development and diseases such as pre-eclampsia. Two transcript variants encoding different isoforms have been found for this gene.
Genomic regions Chromosome 19
Strategy Summary
This gene has 2 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
C19orf33-202 ENST00000588605.5 520 85aa Protein coding CCDS82344 Q9GZP8-2 - TSL:1, GENCODE basic,
C19orf33-201 ENST00000301246.10 374 106aa Protein coding CCDS12511 Q9GZP8-1 NM_033520.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
C19orf33-204 ENST00000591852.1 502 No protein Retained intron - - - TSL:2,
C19orf33-203 ENST00000589986.2 462 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene C19orf33
This KO Strategy loading
Red Cotton™ Notes Gene C19orf33 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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