Official symbol | CCL20 |
Gene id | 6364 |
Organism | Homo sapiens |
Official full symbol | C-C motif chemokine ligand 20 |
Gene type | protein-coding |
Also known as | CKb4, Exodus, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38 |
Summary | This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. |
Genomic regions | Chromosome 2 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
CCL20-202 | ENST00000409189.7 | 839 | 95aa | Protein coding | CCDS46536 | P78556-2 | - | TSL:1, GENCODE basic, APPRIS P4, |
CCL20-201 | ENST00000358813.5 | 834 | 96aa | Protein coding | CCDS2469 | P78556-1 | NM_004591.3 | TSL:1, GENCODE basic, APPRIS ALT1, MANE Select v0.92, |
CCL20-205 | ENST00000646475.1 | 397 | 25aa | Protein coding | - | A0A2R8Y806 | - | CDS 3' incomplete, |
CCL20-203 | ENST00000473642.1 | 680 | No protein | Processed transcript | - | - | - | TSL:2, |
CCL20-204 | ENST00000489160.1 | 673 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | CCL20 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene CCL20 had been KO in hela cell line. |
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