Official symbol | S100A4 |
Gene id | 6275 |
Organism | Homo sapiens |
Official full symbol | S100 calcium binding protein A4 |
Gene type | protein-coding |
Also known as | 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98 |
Summary | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Genomic regions | Chromosome 1 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
S100A4-203 | ENST00000368715.5 | 573 | 101aa | Protein coding | CCDS1042 | P26447 | - | TSL:2, GENCODE basic, APPRIS P1, |
S100A4-201 | ENST00000354332.8 | 566 | 101aa | Protein coding | CCDS1042 | P26447 | - | TSL:1, GENCODE basic, APPRIS P1, |
S100A4-202 | ENST00000368714.1 | 531 | 101aa | Protein coding | CCDS1042 | P26447 | - | TSL:3, GENCODE basic, APPRIS P1, |
S100A4-204 | ENST00000368716.9 | 513 | 101aa | Protein coding | CCDS1042 | P26447 | NM_002961.3 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
S100A4-206 | ENST00000481009.1 | 755 | No protein | Processed transcript | - | - | - | TSL:1, |
S100A4-205 | ENST00000468373.1 | 537 | No protein | Processed transcript | - | - | - | TSL:2, |
Target Gene | S100A4 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene S100A4 had been KO in hela cell line. |
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