CRISPR-U™ Gene Knockout Cell Line Strategy

FKBP10 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human FKBP10 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol FKBP10
Gene id 60681
Organism Homo sapiens
Official full symbol FKBP prolyl isomerase 10
Gene type protein-coding
Also known as BRKS1, FKBP65, OI11, OI6, PPIASE, hFKBP65
Summary The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.
Genomic regions Chromosome 17
Strategy Summary
This gene has 5 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
FKBP10-201 ENST00000321562.9 2585 582aa Protein coding CCDS11409 Q96AY3-1 NM_021939.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
FKBP10-203 ENST00000455106.1 1965 386aa Protein coding - H0Y827 - CDS 5' incomplete, TSL:2,
FKBP10-208 ENST00000585664.5 598 172aa Protein coding - K7ESG6 - CDS 3' incomplete, TSL:3,
FKBP10-209 ENST00000585922.5 563 171aa Protein coding - K7ELI6 - CDS 3' incomplete, TSL:4,
FKBP10-202 ENST00000429461.5 398 81aa Protein coding - C9JPC3 - CDS 3' incomplete, TSL:3,
FKBP10-206 ENST00000489591.5 2826 147aa Nonsense mediated decay - K7EM43 - TSL:2,
FKBP10-204 ENST00000464180.1 1129 No protein Retained intron - - - TSL:2,
FKBP10-207 ENST00000490938.5 837 No protein Retained intron - - - TSL:2,
FKBP10-205 ENST00000487489.1 578 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene FKBP10
This KO Strategy loading
Red Cotton™ Notes Gene FKBP10 had been KO in hek293t cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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