Official symbol | RAD23A |
Gene id | 5886 |
Organism | Homo sapiens |
Official full symbol | RAD23 homolog A, nucleotide excision repair protein |
Gene type | protein-coding |
Also known as | HHR23A, HR23A |
Summary | The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms. |
Genomic regions | Chromosome 19 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
RAD23A-203 | ENST00000586534.6 | 1772 | 363aa | Protein coding | CCDS12289 | P54725-1 | NM_005053.4 | TSL:1, GENCODE basic, APPRIS P4, MANE Select v0.92, |
RAD23A-201 | ENST00000316856.7 | 1736 | 362aa | Protein coding | CCDS59358 | P54725-3 | - | TSL:1, GENCODE basic, APPRIS ALT1, |
RAD23A-209 | ENST00000592268.5 | 1526 | 308aa | Protein coding | CCDS59357 | P54725-2 | - | TSL:5, GENCODE basic, |
RAD23A-206 | ENST00000590881.1 | 999 | 150aa | Protein coding | - | K7EQ16 | - | CDS 5' incomplete, TSL:5, |
RAD23A-211 | ENST00000651137.1 | 1871 | 282aa | Nonsense mediated decay | - | A0A494C0B4 | - | - |
RAD23A-210 | ENST00000593114.5 | 1691 | 139aa | Nonsense mediated decay | - | K7ENJ0 | - | TSL:5, |
RAD23A-208 | ENST00000591499.5 | 1350 | 142aa | Nonsense mediated decay | - | K7ELW1 | - | TSL:2, |
RAD23A-202 | ENST00000586375.1 | 894 | 62aa | Nonsense mediated decay | - | K7ELU6 | - | CDS 5' incomplete, TSL:3, |
RAD23A-205 | ENST00000588826.2 | 832 | No protein | Processed transcript | - | - | - | TSL:5, |
RAD23A-204 | ENST00000588329.5 | 1034 | No protein | Retained intron | - | - | - | TSL:5, |
RAD23A-207 | ENST00000591467.1 | 545 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | RAD23A |
This KO Strategy | loading |
Red Cotton™ Notes | Gene RAD23A had been KO in hek293t cell line. |
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Please leave your suggestion ×