Official symbol | RAB13 |
Gene id | 5872 |
Organism | Homo sapiens |
Official full symbol | RAB13, member RAS oncogene family |
Gene type | protein-coding |
Also known as | GIG4 |
Summary | This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. |
Genomic regions | Chromosome 1 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
RAB13-205 | ENST00000614713.4 | 1353 | 122aa | Protein coding | CCDS72921 | A0A087WWB9 | - | TSL:5, GENCODE basic, |
RAB13-201 | ENST00000368575.5 | 1164 | 203aa | Protein coding | CCDS1058 | P51153 | NM_002870.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
RAB13-202 | ENST00000462680.5 | 2123 | No protein | Processed transcript | - | - | - | TSL:2, |
RAB13-204 | ENST00000495720.5 | 868 | No protein | Processed transcript | - | - | - | TSL:5, |
RAB13-203 | ENST00000484297.1 | 643 | No protein | Processed transcript | - | - | - | TSL:5, |
Target Gene | RAB13 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene RAB13 had been KO in hek293t cell line. |
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