Official symbol | RAB4A |
Gene id | 5867 |
Organism | Homo sapiens |
Official full symbol | RAB4A, member RAS oncogene family |
Gene type | protein-coding |
Also known as | HRES-1, HRES-1/RAB4, HRES1, RAB4 |
Summary | This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. |
Genomic regions | Chromosome 1 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
RAB4A-201 | ENST00000366690.5 | 2987 | 218aa | Protein coding | CCDS31050 | A0A024R3U9 P20338 | NM_004578.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
RAB4A-205 | ENST00000618010.4 | 2799 | 113aa | Protein coding | CCDS73046 | A0A087WYT5 | - | TSL:3, GENCODE basic, |
RAB4A-202 | ENST00000473894.1 | 708 | No protein | Processed transcript | - | - | - | TSL:3, |
RAB4A-204 | ENST00000489342.1 | 431 | No protein | Processed transcript | - | - | - | TSL:5, |
RAB4A-203 | ENST00000481981.1 | 531 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | RAB4A |
This KO Strategy | loading |
Red Cotton™ Notes | Gene RAB4A had been KO in hela cell line. |
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