Official symbol | PRCC |
Gene id | 5546 |
Organism | Homo sapiens |
Official full symbol | proline rich mitotic checkpoint control factor |
Gene type | protein-coding |
Also known as | RCCP1, TPRC |
Summary | This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. |
Genomic regions | Chromosome 1 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
PRCC-201 | ENST00000271526.9 | 2068 | 491aa | Protein coding | CCDS1157 | A0A0S2Z456 Q92733 | NM_005973.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
PRCC-202 | ENST00000454659.1 | 1084 | 257aa | Protein coding | - | H0Y679 | - | CDS 5' incomplete, TSL:3, |
PRCC-207 | ENST00000526188.5 | 634 | 198aa | Protein coding | - | H0YE12 | - | CDS 5' incomplete, TSL:2, |
PRCC-206 | ENST00000491853.5 | 833 | No protein | Processed transcript | - | - | - | TSL:3, |
PRCC-205 | ENST00000473387.1 | 452 | No protein | Processed transcript | - | - | - | TSL:2, |
PRCC-204 | ENST00000469071.1 | 1969 | No protein | Retained intron | - | - | - | TSL:2, |
PRCC-203 | ENST00000459707.1 | 557 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | PRCC |
This KO Strategy | loading |
Red Cotton™ Notes | Gene PRCC had been KO in hek293t cell line. |
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