CRISPR-U™ Gene Knockout Cell Line Strategy

LAMTOR1 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human LAMTOR1 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol LAMTOR1
Gene id 55004
Organism Homo sapiens
Official full symbol late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Gene type protein-coding
Also known as C11orf59, PDRO, Ragulator1, p18, p27RF-Rho
Genomic regions Chromosome 11
Strategy Summary
This gene has 5 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
LAMTOR1-201 ENST00000278671.10 1089 161aa Protein coding CCDS8209 Q6IAA8 NM_017907.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
LAMTOR1-204 ENST00000538404.1 1346 160aa Protein coding - F5H3Y3 - TSL:2, GENCODE basic,
LAMTOR1-208 ENST00000545249.5 965 142aa Protein coding - F5GX19 - TSL:3, GENCODE basic,
LAMTOR1-207 ENST00000544594.5 849 79aa Protein coding - H0YFI1 - CDS 5' incomplete, TSL:3,
LAMTOR1-202 ENST00000535107.5 619 99aa Protein coding - F5H479 - TSL:3, GENCODE basic,
LAMTOR1-203 ENST00000535872.1 899 76aa Nonsense mediated decay - F5H267 - TSL:5,
LAMTOR1-205 ENST00000539797.5 535 No protein Processed transcript - - - TSL:5,
LAMTOR1-206 ENST00000541403.1 566 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene LAMTOR1
This KO Strategy loading
Red Cotton™ Notes Gene LAMTOR1 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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