Official symbol | POLB |
Gene id | 5423 |
Organism | Homo sapiens |
Official full symbol | DNA polymerase beta |
Gene type | protein-coding |
Summary | The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. |
Genomic regions | Chromosome 8 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
POLB-201 | ENST00000265421.9 | 1290 | 335aa | Protein coding | CCDS6129 | P06746 | NM_002690.3 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
POLB-204 | ENST00000518925.5 | 983 | 280aa | Protein coding | - | E7EW18 | - | CDS 3' incomplete, TSL:5, |
POLB-209 | ENST00000521290.5 | 863 | 237aa | Protein coding | - | H0YBJ0 | - | CDS 5' incomplete, TSL:5, |
POLB-211 | ENST00000521492.1 | 786 | 54aa | Protein coding | - | E5RHZ4 | - | TSL:2, GENCODE basic, |
POLB-203 | ENST00000518579.5 | 744 | 239aa | Protein coding | - | H0YBX1 | - | CDS 5' incomplete, TSL:5, |
POLB-208 | ENST00000520008.5 | 725 | 51aa | Protein coding | - | E5RJ55 | - | CDS 3' incomplete, TSL:2, |
POLB-217 | ENST00000532157.5 | 675 | 38aa | Protein coding | - | E9PIC6 | - | CDS 3' incomplete, TSL:3, |
POLB-202 | ENST00000517393.1 | 401 | 106aa | Protein coding | - | H0YAV8 | - | CDS 5' incomplete, TSL:3, |
POLB-213 | ENST00000522610.5 | 1341 | 193aa | Nonsense mediated decay | - | E5RIJ0 | - | TSL:5, |
POLB-207 | ENST00000519771.5 | 720 | 42aa | Nonsense mediated decay | - | E5RG65 | - | TSL:5, |
POLB-215 | ENST00000524208.5 | 653 | 29aa | Nonsense mediated decay | - | H0YB29 | - | CDS 5' incomplete, TSL:5, |
POLB-216 | ENST00000530566.1 | 590 | No protein | Processed transcript | - | - | - | TSL:4, |
POLB-206 | ENST00000519524.1 | 655 | No protein | Retained intron | - | - | - | TSL:5, |
POLB-214 | ENST00000523465.1 | 649 | No protein | Retained intron | - | - | - | TSL:3, |
POLB-210 | ENST00000521418.1 | 628 | No protein | Retained intron | - | - | - | TSL:2, |
POLB-212 | ENST00000522297.1 | 591 | No protein | Retained intron | - | - | - | TSL:2, |
POLB-205 | ENST00000519094.5 | 561 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | POLB |
This KO Strategy | loading |
Red Cotton™ Notes | Gene POLB had been KO in hela cell line. |
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