Official symbol | PIP4K2A |
Gene id | 5305 |
Organism | Homo sapiens |
Official full symbol | phosphatidylinositol-5-phosphate 4-kinase type 2 alpha |
Gene type | protein-coding |
Also known as | PI5P4KA, PIP5K2A, PIP5KII-alpha, PIP5KIIA, PIPK |
Summary | Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. |
Genomic regions | Chromosome 10 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
PIP4K2A-202 | ENST00000376573.9 | 3820 | 406aa | Protein coding | CCDS7141 | P48426-1 | NM_005028.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
PIP4K2A-206 | ENST00000545335.5 | 1436 | 347aa | Protein coding | CCDS81443 | P48426-2 | - | TSL:2, GENCODE basic, |
PIP4K2A-201 | ENST00000323883.11 | 1319 | 266aa | Protein coding | - | H7BXS3 | - | TSL:2, GENCODE basic, |
PIP4K2A-207 | ENST00000604912.1 | 443 | 142aa | Protein coding | - | S4R320 | - | CDS 3' incomplete, TSL:2, |
PIP4K2A-203 | ENST00000422321.5 | 768 | No protein | Processed transcript | - | - | - | TSL:3, |
PIP4K2A-205 | ENST00000474335.1 | 559 | No protein | Processed transcript | - | - | - | TSL:2, |
PIP4K2A-208 | ENST00000605011.1 | 558 | No protein | Processed transcript | - | - | - | TSL:4, |
PIP4K2A-204 | ENST00000432610.1 | 304 | No protein | Processed transcript | - | - | - | TSL:2, |
Target Gene | PIP4K2A |
This KO Strategy | loading |
Red Cotton™ Notes | Gene PIP4K2A had been KO in hela cell line. |
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