CRISPR-U™ Gene Knockout Cell Line Strategy

ETV7 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human ETV7 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol ETV7
Gene id 51513
Organism Homo sapiens
Official full symbol ETS variant transcription factor 7
Gene type protein-coding
Also known as TEL-2, TEL2, TELB
Summary The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).
Genomic regions Chromosome 6
Strategy Summary
This gene has 8 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
ETV7-206 ENST00000615781.4 1776 282aa Protein coding CCDS75440 Q9Y603-2 - TSL:1, GENCODE basic,
ETV7-202 ENST00000340181.9 1605 341aa Protein coding CCDS4819 Q9Y603-1 NM_016135.4 TSL:1, GENCODE basic, APPRIS P2, MANE Select v0.92,
ETV7-207 ENST00000620358.4 1599 260aa Protein coding CCDS75441 Q9Y603-3 - TSL:1, GENCODE basic,
ETV7-204 ENST00000373738.4 1570 286aa Protein coding CCDS56423 Q9Y603-4 - TSL:1, GENCODE basic,
ETV7-201 ENST00000339796.9 1530 317aa Protein coding CCDS56425 Q9Y603-5 - TSL:1, GENCODE basic,
ETV7-203 ENST00000373737.8 1488 264aa Protein coding CCDS56424 Q9Y603-7 - TSL:1, GENCODE basic, APPRIS ALT2,
ETV7-205 ENST00000538992.3 1434 190aa Protein coding CCDS56422 Q9Y603-8 - TSL:2, GENCODE basic,
ETV7-208 ENST00000627426.2 1285 262aa Protein coding CCDS78131 Q9Y603-6 - TSL:1, GENCODE basic,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene ETV7
This KO Strategy loading
Red Cotton™ Notes Gene ETV7 had been KO in a549 cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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