CRISPR-U™ Gene Knockout Cell Line Strategy

ERGIC2 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human ERGIC2 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol ERGIC2
Gene id 51290
Organism Homo sapiens
Official full symbol ERGIC and golgi 2
Gene type protein-coding
Also known as CDA14, Erv41, PTX1, cd002
Summary ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 ).
Genomic regions Chromosome 12
Strategy Summary
This gene has 9 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
ERGIC2-201 ENST00000360150.9 5033 377aa Protein coding CCDS41765 A0A024RB08 Q96RQ1 NM_016570.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
ERGIC2-212 ENST00000611644.4 4961 386aa Protein coding - A0A087WU02 - TSL:5, GENCODE basic,
ERGIC2-203 ENST00000546839.5 1274 220aa Protein coding - F8VPA6 - CDS 3' incomplete, TSL:5,
ERGIC2-209 ENST00000551467.5 765 209aa Protein coding - H0YI50 - CDS 5' incomplete, TSL:5,
ERGIC2-210 ENST00000552132.5 695 175aa Protein coding - F8VR88 - CDS 3' incomplete, TSL:3,
ERGIC2-211 ENST00000552155.5 693 203aa Protein coding - F8VUZ2 - CDS 3' incomplete, TSL:3,
ERGIC2-206 ENST00000548909.5 645 163aa Protein coding - H0YI58 - CDS 5' incomplete, TSL:5,
ERGIC2-208 ENST00000550353.5 616 172aa Protein coding - F8W0R1 - CDS 3' incomplete, TSL:5,
ERGIC2-205 ENST00000548441.1 432 71aa Protein coding - F8VRW9 - CDS 3' incomplete, TSL:3,
ERGIC2-207 ENST00000549182.1 565 49aa Nonsense mediated decay - H0YHS0 - CDS 5' incomplete, TSL:5,
ERGIC2-202 ENST00000546509.5 308 57aa Nonsense mediated decay - H0YHJ8 - CDS 5' incomplete, TSL:3,
ERGIC2-204 ENST00000548098.1 318 No protein Retained intron - - - TSL:2,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene ERGIC2
This KO Strategy loading
Red Cotton™ Notes Gene ERGIC2 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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