CRISPR-U™ Gene Knockout Cell Line Strategy

CDK17 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human CDK17 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol CDK17
Gene id 5128
Organism Homo sapiens
Official full symbol cyclin dependent kinase 17
Gene type protein-coding
Also known as PCTAIRE2, PCTK2
Summary The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found.
Genomic regions Chromosome 12
Strategy Summary
This gene has 7 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
CDK17-201 ENST00000261211.8 4036 523aa Protein coding CCDS9061 Q00537-1 NM_002595.5 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
CDK17-203 ENST00000543119.6 2442 523aa Protein coding CCDS53819 Q00537-2 - TSL:2, GENCODE basic,
CDK17-202 ENST00000542666.5 1769 470aa Protein coding - F5H6Z0 - TSL:2, GENCODE basic,
CDK17-209 ENST00000551816.5 626 179aa Protein coding - F8VQZ9 - CDS 3' incomplete, TSL:4,
CDK17-211 ENST00000552496.5 583 161aa Protein coding - F8VZY6 - CDS 3' incomplete, TSL:3,
CDK17-210 ENST00000552262.1 566 88aa Protein coding - F8VUX2 - CDS 3' incomplete, TSL:3,
CDK17-205 ENST00000548734.1 556 129aa Protein coding - F8W1S5 - CDS 3' incomplete, TSL:4,
CDK17-212 ENST00000553042.1 569 No protein Processed transcript - - - TSL:4,
CDK17-207 ENST00000550971.5 482 No protein Processed transcript - - - TSL:3,
CDK17-204 ENST00000548422.1 892 No protein Retained intron - - - TSL:3,
CDK17-208 ENST00000551484.1 575 No protein Retained intron - - - TSL:4,
CDK17-206 ENST00000549899.1 506 No protein Retained intron - - - TSL:5,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene CDK17
This KO Strategy loading
Red Cotton™ Notes Gene CDK17 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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