Official symbol | ASAP1 |
Gene id | 50807 |
Organism | Homo sapiens |
Official full symbol | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
Gene type | protein-coding |
Also known as | AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P |
Summary | This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Genomic regions | Chromosome 8 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
ASAP1-201 | ENST00000357668.2 | 6344 | 1122aa | Protein coding | CCDS75788 | A0A0A0MRE5 | - | TSL:5, GENCODE basic, APPRIS ALT2, |
ASAP1-202 | ENST00000518721.6 | 6259 | 1129aa | Protein coding | CCDS6362 | Q9ULH1-1 | NM_018482.4 | TSL:5, GENCODE basic, APPRIS P4, MANE Select v0.92, |
ASAP1-214 | ENST00000524124.5 | 5478 | 950aa | Protein coding | - | H0YBF7 | - | CDS 5' incomplete, TSL:1, |
ASAP1-205 | ENST00000519483.5 | 1449 | 483aa | Protein coding | - | H0YBM4 | - | CDS 5' and 3' incomplete, TSL:5, |
ASAP1-207 | ENST00000520342.5 | 566 | 33aa | Protein coding | - | E5RFD9 | - | CDS 3' incomplete, TSL:5, |
ASAP1-212 | ENST00000521426.5 | 566 | 98aa | Protein coding | - | E5RHD7 | - | CDS 3' incomplete, TSL:4, |
ASAP1-211 | ENST00000521075.5 | 5406 | 39aa | Nonsense mediated decay | - | E5RHA9 | - | TSL:1, |
ASAP1-209 | ENST00000520927.5 | 742 | 39aa | Nonsense mediated decay | - | E5RHA9 | - | TSL:5, |
ASAP1-215 | ENST00000524299.1 | 550 | 39aa | Nonsense mediated decay | - | E5RHA9 | - | TSL:4, |
ASAP1-216 | ENST00000524367.5 | 962 | No protein | Processed transcript | - | - | - | TSL:5, |
ASAP1-208 | ENST00000520625.1 | 606 | No protein | Processed transcript | - | - | - | TSL:3, |
ASAP1-203 | ENST00000518957.1 | 446 | No protein | Processed transcript | - | - | - | TSL:3, |
ASAP1-210 | ENST00000521057.1 | 720 | No protein | Retained intron | - | - | - | TSL:3, |
ASAP1-204 | ENST00000519169.5 | 708 | No protein | Retained intron | - | - | - | TSL:2, |
ASAP1-206 | ENST00000520189.1 | 572 | No protein | Retained intron | - | - | - | TSL:4, |
ASAP1-213 | ENST00000524018.1 | 401 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | ASAP1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene ASAP1 had been KO in hela cell line. |
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