CRISPR-U™ Gene Knockout Cell Line Strategy

IL20 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human IL20 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol IL20
Gene id 50604
Organism Homo sapiens
Official full symbol interleukin 20
Gene type protein-coding
Also known as IL-20, IL10D, ZCYTO10
Summary The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Genomic regions Chromosome 1
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
IL20-202 ENST00000367098.6 1284 176aa Protein coding CCDS1470 Q9NYY1-1 NM_018724.4 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
IL20-201 ENST00000367096.7 925 176aa Protein coding CCDS1470 Q9NYY1-1 - TSL:1, GENCODE basic, APPRIS P1,
IL20-203 ENST00000391930.3 1153 151aa Protein coding - Q9NYY1-2 - TSL:1, GENCODE basic,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene IL20
This KO Strategy loading
Red Cotton™ Notes Gene IL20 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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