Official symbol | NFATC3 |
Gene id | 4775 |
Organism | Homo sapiens |
Official full symbol | nuclear factor of activated T cells 3 |
Gene type | protein-coding |
Also known as | NF-AT4c, NFAT4, NFATX |
Summary | The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. |
Genomic regions | Chromosome 16 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
NFATC3-202 | ENST00000346183.8 | 6328 | 1075aa | Protein coding | CCDS10860 | Q12968-1 | NM_173165.3 | TSL:1, GENCODE basic, APPRIS ALT1, MANE Select v0.92, |
NFATC3-203 | ENST00000349223.9 | 6328 | 1065aa | Protein coding | CCDS10861 | Q12968-3 | - | TSL:1, GENCODE basic, |
NFATC3-201 | ENST00000329524.8 | 6144 | 1068aa | Protein coding | CCDS10862 | Q12968-2 | - | TSL:1, GENCODE basic, APPRIS P4, |
NFATC3-222 | ENST00000575270.5 | 3824 | 1047aa | Protein coding | - | I3L3K7 | - | TSL:5, GENCODE basic, |
NFATC3-211 | ENST00000562926.5 | 3748 | 1053aa | Protein coding | - | H3BR83 | - | CDS 5' incomplete, TSL:1, |
NFATC3-221 | ENST00000570212.5 | 3181 | 1060aa | Protein coding | - | H3BRS1 | - | CDS 5' incomplete, TSL:1, |
NFATC3-215 | ENST00000565750.2 | 529 | 167aa | Protein coding | - | H3BU30 | - | CDS 5' incomplete, TSL:3, |
NFATC3-206 | ENST00000539828.6 | 2484 | 38aa | Nonsense mediated decay | - | F8VPH9 | - | TSL:2, |
NFATC3-209 | ENST00000561714.5 | 792 | 38aa | Nonsense mediated decay | - | F8VPH9 | - | TSL:3, |
NFATC3-219 | ENST00000568466.6 | 737 | 38aa | Nonsense mediated decay | - | F8VPH9 | - | TSL:2, |
NFATC3-210 | ENST00000562171.1 | 707 | 41aa | Nonsense mediated decay | - | H3BRM3 | - | TSL:3, |
NFATC3-205 | ENST00000535127.2 | 4194 | No protein | Processed transcript | - | - | - | TSL:1, |
NFATC3-213 | ENST00000563319.5 | 4122 | No protein | Processed transcript | - | - | - | TSL:1, |
NFATC3-216 | ENST00000566301.5 | 3840 | No protein | Processed transcript | - | - | - | TSL:1, |
NFATC3-212 | ENST00000563288.5 | 3790 | No protein | Processed transcript | - | - | - | TSL:1, |
NFATC3-214 | ENST00000563796.5 | 3753 | No protein | Processed transcript | - | - | - | TSL:1, |
NFATC3-220 | ENST00000569766.5 | 3555 | No protein | Processed transcript | - | - | - | TSL:1, |
NFATC3-218 | ENST00000567152.5 | 3186 | No protein | Processed transcript | - | - | - | TSL:1, |
NFATC3-217 | ENST00000566893.5 | 715 | No protein | Processed transcript | - | - | - | TSL:2, |
NFATC3-208 | ENST00000553077.5 | 3870 | No protein | Retained intron | - | - | - | TSL:2, |
NFATC3-207 | ENST00000549350.5 | 3588 | No protein | Retained intron | - | - | - | TSL:2, |
NFATC3-204 | ENST00000379165.8 | 3583 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | NFATC3 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene NFATC3 had been KO in hek293t cell line. |
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