Official symbol | MX2 |
Gene id | 4600 |
Organism | Homo sapiens |
Official full symbol | MX dynamin like GTPase 2 |
Gene type | protein-coding |
Also known as | MXB |
Summary | The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. |
Genomic regions | Chromosome 21 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
MX2-216 | ENST00000680862.1 | 3509 | 715aa | Protein coding | CCDS13672 | - | - | GENCODE basic, APPRIS P1, |
MX2-205 | ENST00000435611.6 | 3485 | 715aa | Protein coding | CCDS13672 | C9JS04 | - | TSL:3, GENCODE basic, APPRIS P1, |
MX2-201 | ENST00000330714.8 | 3408 | 715aa | Protein coding | CCDS13672 | P20592-1 | NM_002463.2 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
MX2-203 | ENST00000416447.1 | 843 | 14aa | Protein coding | - | C9J9T4 | - | CDS 3' incomplete, TSL:5, |
MX2-206 | ENST00000436410.5 | 582 | 129aa | Protein coding | - | C9JZQ9 | - | CDS 3' incomplete, TSL:3, |
MX2-204 | ENST00000418103.2 | 1257 | 201aa | Nonsense mediated decay | - | C9JEL4 | - | TSL:3, |
MX2-208 | ENST00000481838.5 | 562 | 96aa | Nonsense mediated decay | - | - | - | CDS 5' incomplete, TSL:1, |
MX2-218 | ENST00000681460.1 | 1893 | No protein | Processed transcript | - | - | - | - |
MX2-211 | ENST00000494252.1 | 440 | No protein | Processed transcript | - | - | - | TSL:3, |
MX2-212 | ENST00000495892.1 | 4064 | No protein | Retained intron | - | - | - | TSL:2, |
MX2-209 | ENST00000482953.5 | 3595 | No protein | Retained intron | - | - | - | TSL:2, |
MX2-215 | ENST00000680539.1 | 3113 | No protein | Retained intron | - | - | - | - |
MX2-207 | ENST00000474368.1 | 2871 | No protein | Retained intron | - | - | - | TSL:2, |
MX2-214 | ENST00000680215.1 | 2366 | No protein | Retained intron | - | - | - | - |
MX2-202 | ENST00000398632.3 | 2211 | No protein | Retained intron | - | - | - | TSL:2, |
MX2-217 | ENST00000681171.1 | 2060 | No protein | Retained intron | - | - | - | - |
MX2-210 | ENST00000493753.2 | 1900 | No protein | Retained intron | - | - | - | TSL:3, |
MX2-213 | ENST00000496774.5 | 827 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | MX2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene MX2 had been KO in a549 cell line. |
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Please leave your suggestion ×