CRISPR-U™ Gene Knockout Cell Line
Strategy
MEOX1 Gene Knockout Strategy
CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general
CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has
successfully edited over 3000 genes on more than 100 types of cell lines.
Objective
To create a Human MEOX1 Knockout
model in cell line by
CRISPR-U™-mediated
genome
engineering.
Target gene info 
| Official symbol | MEOX1 |
| Gene id | 4222 |
| Organism | Homo sapiens |
| Official full symbol | mesenchyme homeobox 1 |
| Gene type | protein-coding |
| Also known as | KFS2, MOX1 |
| Summary | This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Genomic regions | Chromosome 17 |
Strategy Summary
This gene has 3 protein coding transcripts：
| Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
| MEOX1-201 | ENST00000318579.9 | 2674 | 254aa | Protein coding | CCDS11466 | P50221-1 | NM_004527.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
| MEOX1-202 | ENST00000393661.2 | 1206 | 139aa | Protein coding | CCDS42343 | P50221-3 | - | TSL:3, GENCODE basic, |
| MEOX1-203 | ENST00000549132.2 | 1152 | 184aa | Protein coding | CCDS11467 | P50221-2 | - | TSL:1, GENCODE basic, |
Strategy
Click to get
Red Cotton™ Assessment
Project Difficulty Level unknown
| Target Gene | MEOX1 |
| This KO Strategy | loading |
| Red Cotton™ Notes | Gene MEOX1 had been KO in hela cell line. |
Aforementioned information comes from Ubigene database. Different origin of cell lines may have
different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:
$49
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Work flow
Comment: