CRISPR-U™ Gene Knockout Cell Line Strategy

MAGEA6 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human MAGEA6 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol MAGEA6
Gene id 4105
Organism Homo sapiens
Official full symbol MAGE family member A6
Gene type protein-coding
Also known as CT1.6, MAGE-3b, MAGE3B, MAGE6
Summary This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Genomic regions Chromosome X
Strategy Summary
This gene has 4 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
MAGEA6-204 ENST00000616035.4 1762 314aa Protein coding CCDS76050 P43360 - TSL:5, GENCODE basic, APPRIS P1,
MAGEA6-201 ENST00000329342.9 1740 314aa Protein coding CCDS76050 P43360 - TSL:1, GENCODE basic, APPRIS P1,
MAGEA6-203 ENST00000457643.1 921 235aa Protein coding - E7ETG4 - CDS 3' incomplete, TSL:3,
MAGEA6-202 ENST00000412733.1 862 201aa Protein coding - E7EUF2 - CDS 3' incomplete, TSL:5,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene MAGEA6
This KO Strategy loading
Red Cotton™ Notes Gene MAGEA6 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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