Official symbol | ASIC1 |
Gene id | 41 |
Organism | Homo sapiens |
Official full symbol | acid sensing ion channel subunit 1 |
Gene type | protein-coding |
Also known as | ACCN2, ASIC, BNaC2 |
Summary | This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. |
Genomic regions | Chromosome 12 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
ASIC1-201 | ENST00000228468.8 | 4072 | 574aa | Protein coding | CCDS8796 | P78348-1 | - | TSL:1, GENCODE basic, |
ASIC1-202 | ENST00000447966.7 | 3886 | 528aa | Protein coding | CCDS44876 | P78348-2 | NM_001095.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
ASIC1-208 | ENST00000552438.5 | 3327 | 562aa | Protein coding | CCDS58228 | P78348-3 | - | TSL:1, GENCODE basic, |
ASIC1-203 | ENST00000453327.7 | 1481 | 396aa | Protein coding | - | H7C1W9 | - | CDS 5' incomplete, TSL:2, |
ASIC1-209 | ENST00000552633.2 | 614 | 127aa | Protein coding | - | H0YHD6 | - | CDS 5' incomplete, TSL:5, |
ASIC1-206 | ENST00000550558.5 | 3819 | 263aa | Nonsense mediated decay | - | F8VSK4 | - | TSL:2, |
ASIC1-207 | ENST00000551199.1 | 1223 | No protein | Retained intron | - | - | - | TSL:2, |
ASIC1-204 | ENST00000548350.1 | 560 | No protein | Retained intron | - | - | - | TSL:4, |
ASIC1-205 | ENST00000549792.1 | 350 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | ASIC1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene ASIC1 had been KO in hela cell line. |
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