Official symbol | LTBR |
Gene id | 4055 |
Organism | Homo sapiens |
Official full symbol | lymphotoxin beta receptor |
Gene type | protein-coding |
Also known as | D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3 |
Summary | This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. |
Genomic regions | Chromosome 12 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
LTBR-201 | ENST00000228918.9 | 2134 | 435aa | Protein coding | CCDS8544 | P36941-1 | NM_002342.3 | TSL:1, GENCODE basic, APPRIS P2, MANE Select v0.92, |
LTBR-207 | ENST00000539925.5 | 1665 | 416aa | Protein coding | CCDS59233 | P36941-2 | - | TSL:2, GENCODE basic, APPRIS ALT2, |
LTBR-209 | ENST00000541102.1 | 1084 | 292aa | Protein coding | - | F5H2E7 | - | TSL:5, GENCODE basic, |
LTBR-206 | ENST00000536876.5 | 842 | 217aa | Protein coding | - | F5H6F8 | - | CDS 3' incomplete, TSL:5, |
LTBR-211 | ENST00000543190.5 | 785 | 74aa | Protein coding | - | F5H1S5 | - | TSL:3, GENCODE basic, |
LTBR-213 | ENST00000544454.5 | 632 | 148aa | Nonsense mediated decay | - | F5H627 | - | TSL:5, |
LTBR-215 | ENST00000546296.5 | 783 | No protein | Processed transcript | - | - | - | TSL:4, |
LTBR-210 | ENST00000542830.5 | 539 | No protein | Processed transcript | - | - | - | TSL:4, |
LTBR-203 | ENST00000441074.3 | 2327 | No protein | Retained intron | - | - | - | TSL:1, |
LTBR-204 | ENST00000444814.2 | 1553 | No protein | Retained intron | - | - | - | TSL:2, |
LTBR-205 | ENST00000535739.5 | 928 | No protein | Retained intron | - | - | - | TSL:5, |
LTBR-202 | ENST00000440421.2 | 729 | No protein | Retained intron | - | - | - | TSL:2, |
LTBR-208 | ENST00000541005.1 | 583 | No protein | Retained intron | - | - | - | TSL:2, |
LTBR-214 | ENST00000545445.1 | 379 | No protein | Retained intron | - | - | - | TSL:2, |
LTBR-212 | ENST00000543542.1 | 367 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | LTBR |
This KO Strategy | loading |
Red Cotton™ Notes | Gene LTBR had been KO in hela cell line. |
$49
Single gRNA plasmid off-shelf
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Single gRNA lentivirus
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