Official symbol | IFIT1 |
Gene id | 3434 |
Organism | Homo sapiens |
Official full symbol | interferon induced protein with tetratricopeptide repeats 1 |
Gene type | protein-coding |
Also known as | C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561 |
Summary | This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. |
Genomic regions | Chromosome 10 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
IFIT1-202 | ENST00000546318.2 | 4613 | 447aa | Protein coding | CCDS59220 | P09914-2 | - | TSL:3, GENCODE basic, |
IFIT1-201 | ENST00000371804.4 | 4302 | 478aa | Protein coding | CCDS31243 | P09914-1 | NM_001548.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
Target Gene | IFIT1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene IFIT1 had been KO in a549 cell line. |
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