CRISPR-U™ Gene Knockout Cell Line Strategy

CCDC137 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human CCDC137 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol CCDC137
Gene id 339230
Organism Homo sapiens
Official full symbol coiled-coil domain containing 137
Gene type protein-coding
Also known as RaRF
Genomic regions Chromosome 17
Strategy Summary
This gene has 2 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
CCDC137-201 ENST00000329214.13 2095 289aa Protein coding CCDS42400 Q6PK04 NM_199287.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
CCDC137-204 ENST00000574107.1 890 292aa Protein coding - I3L0U5 - CDS 3' incomplete, TSL:3,
CCDC137-206 ENST00000575223.5 1888 289aa Nonsense mediated decay CCDS42400 Q6PK04 - TSL:5,
CCDC137-202 ENST00000571916.1 708 61aa Nonsense mediated decay - I3L385 - CDS 5' incomplete, TSL:3,
CCDC137-205 ENST00000574200.1 437 44aa Nonsense mediated decay - I3L4F6 - CDS 5' incomplete, TSL:2,
CCDC137-203 ENST00000572531.1 265 No protein Retained intron - - - TSL:3,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene CCDC137
This KO Strategy loading
Red Cotton™ Notes Gene CCDC137 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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