Official symbol | FOXA2 |
Gene id | 3170 |
Organism | Homo sapiens |
Official full symbol | forkhead box A2 |
Gene type | protein-coding |
Also known as | HNF-3-beta, HNF3B, TCF3B |
Summary | This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. |
Genomic regions | Chromosome 20 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
FOXA2-202 | ENST00000419308.7 | 2538 | 463aa | Protein coding | CCDS46585 | Q9Y261-2 | NM_021784.5 | TSL:1, GENCODE basic, APPRIS P4, MANE Select v0.92, |
FOXA2-201 | ENST00000377115.4 | 2401 | 457aa | Protein coding | CCDS13147 | Q9Y261-1 | - | TSL:1, GENCODE basic, APPRIS ALT1, |
Target Gene | FOXA2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene FOXA2 had been KO in hela cell line. |
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