Official symbol | HMGB1 |
Gene id | 3146 |
Organism | Homo sapiens |
Official full symbol | high mobility group box 1 |
Gene type | protein-coding |
Also known as | HMG-1, HMG1, HMG3, SBP-1 |
Summary | This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. |
Genomic regions | Chromosome 13 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
HMGB1-203 | ENST00000341423.10 | 5456 | 215aa | Protein coding | CCDS9335 | A0A024RDR0 P09429 | NM_002128.7 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
HMGB1-206 | ENST00000405805.5 | 4199 | 215aa | Protein coding | CCDS9335 | A0A024RDR0 P09429 | - | TSL:2, GENCODE basic, APPRIS P1, |
HMGB1-202 | ENST00000339872.8 | 2319 | 215aa | Protein coding | CCDS9335 | A0A024RDR0 P09429 | - | TSL:2, GENCODE basic, APPRIS P1, |
HMGB1-204 | ENST00000399489.5 | 1727 | 158aa | Protein coding | CCDS86347 | Q5T7C4 | - | TSL:1, GENCODE basic, |
HMGB1-205 | ENST00000399494.5 | 1282 | 215aa | Protein coding | CCDS9335 | A0A024RDR0 P09429 | - | TSL:2, GENCODE basic, APPRIS P1, |
HMGB1-201 | ENST00000326004.4 | 821 | 158aa | Protein coding | CCDS86347 | Q5T7C4 | - | TSL:3, GENCODE basic, |
HMGB1-207 | ENST00000468384.1 | 503 | No protein | Processed transcript | - | - | - | TSL:1, |
HMGB1-208 | ENST00000490788.1 | 425 | No protein | Processed transcript | - | - | - | TSL:2, |
Target Gene | HMGB1 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene HMGB1 had been KO in hela cell line. |
$39
Single gRNA plasmid off-shelf
$599
Single gRNA lentivirus
Please leave your suggestion ×