Official symbol | HELLS |
Gene id | 3070 |
Organism | Homo sapiens |
Official full symbol | helicase, lymphoid specific |
Gene type | protein-coding |
Also known as | ICF4, LSH, Nbla10143, PASG, SMARCA6 |
Summary | This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Genomic regions | Chromosome 10 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
HELLS-205 | ENST00000394036.5 | 3131 | 884aa | Protein coding | CCDS73162 | A0A0B4J1V9 | - | TSL:1, GENCODE basic, |
HELLS-202 | ENST00000348459.10 | 3128 | 838aa | Protein coding | CCDS7434 | Q9NRZ9-1 | NM_018063.5 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
HELLS-201 | ENST00000239026.10 | 2740 | 714aa | Protein coding | CCDS73165 | F6XU50 | - | TSL:5, GENCODE basic, |
HELLS-206 | ENST00000394045.5 | 2699 | 740aa | Protein coding | CCDS73163 | Q9NRZ9-5 | - | TSL:1, GENCODE basic, |
HELLS-204 | ENST00000371332.8 | 2675 | 700aa | Protein coding | CCDS73164 | A0A087WSW7 | - | TSL:5, GENCODE basic, |
HELLS-203 | ENST00000371327.2 | 4987 | 310aa | Protein coding | - | Q9NW36 | - | CDS 5' incomplete, TSL:2, |
HELLS-207 | ENST00000419900.5 | 711 | 192aa | Protein coding | - | B1ALG6 | - | CDS 3' incomplete, TSL:3, |
HELLS-212 | ENST00000630929.2 | 400 | 97aa | Protein coding | - | Q76H82 | - | TSL:5, GENCODE basic, |
HELLS-208 | ENST00000462057.2 | 778 | No protein | Processed transcript | - | - | - | TSL:3, |
HELLS-210 | ENST00000466552.1 | 2724 | No protein | Retained intron | - | - | - | TSL:2, |
HELLS-211 | ENST00000475263.1 | 676 | No protein | Retained intron | - | - | - | TSL:3, |
HELLS-209 | ENST00000464030.1 | 321 | No protein | Retained intron | - | - | - | TSL:3, |
Target Gene | HELLS |
This KO Strategy | loading |
Red Cotton™ Notes | Gene HELLS had been KO in hct116 cell line. |
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