Official symbol | MRPS28 |
Gene id | 28957 |
Organism | Homo sapiens |
Official full symbol | mitochondrial ribosomal protein S28 |
Gene type | protein-coding |
Also known as | COXPD47, HSPC007, MRP-S28, MRP-S35, MRPS35 |
Summary | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature. |
Genomic regions | Chromosome 8 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
MRPS28-201 | ENST00000276585.9 | 838 | 187aa | Protein coding | CCDS6226 | A0A0S2Z563 Q9Y2Q9 | NM_014018.3 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
MRPS28-203 | ENST00000518371.2 | 783 | 83aa | Protein coding | - | U3KQQ8 | - | CDS 5' incomplete, TSL:3, |
MRPS28-207 | ENST00000521434.5 | 585 | 125aa | Protein coding | - | E5RFH3 | - | TSL:5, GENCODE basic, |
MRPS28-205 | ENST00000519386.5 | 555 | 143aa | Protein coding | - | H0YAT2 | - | CDS 5' incomplete, TSL:2, |
MRPS28-202 | ENST00000518271.1 | 487 | 162aa | Protein coding | - | H7C5V3 | - | CDS 5' and 3' incomplete, TSL:5, |
MRPS28-208 | ENST00000521605.1 | 437 | 86aa | Protein coding | - | E5RFT8 | - | TSL:2, GENCODE basic, |
MRPS28-206 | ENST00000520946.1 | 411 | 108aa | Protein coding | - | E5RK86 | - | CDS 3' incomplete, TSL:5, |
MRPS28-204 | ENST00000519120.1 | 403 | 103aa | Protein coding | - | E5RGC7 | - | CDS 3' incomplete, TSL:2, |
MRPS28-209 | ENST00000522987.1 | 487 | No protein | Processed transcript | - | - | - | TSL:3, |
Target Gene | MRPS28 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene MRPS28 had been KO in hek293t cell line. |
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