CRISPR-U™ Gene Knockout Cell Line Strategy

LAMP3 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human LAMP3 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol LAMP3
Gene id 27074
Organism Homo sapiens
Official full symbol lysosomal associated membrane protein 3
Gene type protein-coding
Also known as CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403
Summary Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 ).
Genomic regions Chromosome 3
Strategy Summary
This gene has 4 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
LAMP3-201 ENST00000265598.8 3196 416aa Protein coding CCDS3242 Q9UQV4 NM_014398.4 TSL:1, GENCODE basic, APPRIS P2, MANE Select v0.92,
LAMP3-202 ENST00000466939.1 1453 392aa Protein coding - E7ETP9 - TSL:2, GENCODE basic, APPRIS ALT2,
LAMP3-204 ENST00000476015.1 835 180aa Protein coding - C9JYP5 - CDS 3' incomplete, TSL:4,
LAMP3-203 ENST00000470251.1 829 143aa Protein coding - C9JDI8 - CDS 3' incomplete, TSL:2,
LAMP3-205 ENST00000486686.1 469 No protein Processed transcript - - - TSL:5,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene LAMP3
This KO Strategy loading
Red Cotton™ Notes Gene LAMP3 had been KO in a549 cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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