Official symbol | GDI2 |
Gene id | 2665 |
Organism | Homo sapiens |
Official full symbol | GDP dissociation inhibitor 2 |
Gene type | protein-coding |
Also known as | HEL-S-46e, RABGDIB |
Summary | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Genomic regions | Chromosome 10 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
GDI2-203 | ENST00000380191.9 | 2297 | 445aa | Protein coding | CCDS7071 | P50395-1 | NM_001494.4 | TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92, |
GDI2-202 | ENST00000380181.7 | 1408 | 400aa | Protein coding | CCDS44352 | P50395-2 | - | TSL:1, GENCODE basic, |
GDI2-206 | ENST00000456041.5 | 918 | 263aa | Protein coding | - | Q5SX87 | - | CDS 3' incomplete, TSL:5, |
GDI2-205 | ENST00000447751.5 | 834 | 203aa | Protein coding | - | Q5SX91 | - | CDS 5' incomplete, TSL:3, |
GDI2-204 | ENST00000418688.5 | 636 | 155aa | Protein coding | - | Q5SX86 | - | CDS 3' incomplete, TSL:5, |
GDI2-208 | ENST00000608581.5 | 634 | 130aa | Protein coding | - | V9GYF8 | - | CDS 3' incomplete, TSL:3, |
GDI2-209 | ENST00000609712.1 | 622 | 125aa | Protein coding | - | V9GYJ7 | - | CDS 3' incomplete, TSL:3, |
GDI2-201 | ENST00000380127.5 | 584 | 148aa | Protein coding | - | Q5SX90 | - | CDS 3' incomplete, TSL:3, |
GDI2-207 | ENST00000479928.1 | 2499 | No protein | Processed transcript | - | - | - | TSL:2, |
Target Gene | GDI2 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene GDI2 had been KO in hek293t cell line. |
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