Official symbol | GATA4 |
Gene id | 2626 |
Organism | Homo sapiens |
Official full symbol | GATA binding protein 4 |
Gene type | protein-coding |
Also known as | ASD2, TACHD, TOF, VSD1 |
Summary | This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. |
Genomic regions | Chromosome 8 |
Name | Transcript ID | bp | Protein | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
GATA4-207 | ENST00000532059.6 | 3419 | 443aa | Protein coding | CCDS78303 | P43694-2 | NM_001308093.3 | TSL:1, GENCODE basic, APPRIS P4, MANE Select v0.92, |
GATA4-201 | ENST00000335135.8 | 3414 | 442aa | Protein coding | CCDS5983 | P43694-1 | - | TSL:5, GENCODE basic, APPRIS ALT1, |
GATA4-206 | ENST00000528712.5 | 2614 | 236aa | Protein coding | CCDS78304 | B3KUF4 | - | TSL:2, GENCODE basic, |
GATA4-209 | ENST00000622443.2 | 1982 | 441aa | Protein coding | - | A0A087WZ09 | - | TSL:5, GENCODE basic, |
GATA4-205 | ENST00000528027.1 | 1010 | 116aa | Protein coding | - | E9PRI5 | - | CDS 3' incomplete, TSL:2, |
GATA4-208 | ENST00000532977.1 | 877 | 16aa | Protein coding | - | B6DU75 | - | CDS 3' incomplete, TSL:1, |
GATA4-204 | ENST00000526974.1 | 832 | 23aa | Protein coding | - | R4GND5 | - | CDS 3' incomplete, TSL:2, |
GATA4-203 | ENST00000526716.5 | 686 | 175aa | Protein coding | - | E9PKS4 | - | CDS 3' incomplete, TSL:4, |
GATA4-202 | ENST00000526021.1 | 1064 | No protein | Retained intron | - | - | - | TSL:2, |
Target Gene | GATA4 |
This KO Strategy | loading |
Red Cotton™ Notes | Gene GATA4 had been KO in hek293t cell line. |
$49
Single gRNA plasmid off-shelf
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Single gRNA lentivirus
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