CRISPR-U™ Gene Knockout Cell Line Strategy

DSTYK Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human DSTYK Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol DSTYK
Gene id 25778
Organism Homo sapiens
Official full symbol dual serine/threonine and tyrosine protein kinase
Gene type protein-coding
Also known as CAKUT1, DustyPK, HDCMD38P, RIP5, RIPK5, SPG23
Summary This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Genomic regions Chromosome 1
Strategy Summary
This gene has 3 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
DSTYK-202 ENST00000367162.8 8010 929aa Protein coding CCDS1451 Q6XUX3-1 NM_015375.3 TSL:1, GENCODE basic, APPRIS P1, MANE Select v0.92,
DSTYK-201 ENST00000367161.7 7739 884aa Protein coding CCDS1452 Q6XUX3-2 - TSL:1, GENCODE basic,
DSTYK-203 ENST00000615388.1 1042 179aa Protein coding - Q6XUX3-4 - TSL:5, GENCODE basic,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene DSTYK
This KO Strategy loading
Red Cotton™ Notes Gene DSTYK had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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