CRISPR-U™ Gene Knockout Cell Line Strategy

MTCH1 Gene Knockout Strategy

CRISPR-U™ technology (CRISPR based), developed by Ubigene, is more efficient than general CRISPR/Cas9 technology in double-strand breaking and homologous recombination. With CRISPR-U™, Ubigene has successfully edited over 3000 genes on more than 100 types of cell lines.
To create a Human MTCH1 Knockout model in cell line by CRISPR-U™-mediated genome engineering.
Target gene info
Official symbol MTCH1
Gene id 23787
Organism Homo sapiens
Official full symbol mitochondrial carrier 1
Gene type protein-coding
Also known as CGI-64, PIG60, PSAP, SLC25A49
Summary This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Genomic regions Chromosome 6
Strategy Summary
This gene has 4 protein coding transcripts:
Name Transcript ID bp Protein Biotype CCDS UniProt Match RefSeq Match Flags
MTCH1-201 ENST00000373616.9 2006 372aa Protein coding CCDS4828 Q9NZJ7-2 - TSL:1, GENCODE basic, APPRIS ALT1,
MTCH1-202 ENST00000373627.10 1955 389aa Protein coding CCDS64411 Q9NZJ7-1 NM_001271641.2 TSL:1, GENCODE basic, APPRIS P4, MANE Select v0.92,
MTCH1-204 ENST00000460219.2 1572 394aa Protein coding - H0Y8C3 - CDS 5' incomplete, TSL:2,
MTCH1-203 ENST00000418541.6 602 201aa Protein coding - H7C196 - CDS 5' and 3' incomplete, TSL:3,
MTCH1-205 ENST00000471737.1 629 No protein Processed transcript - - - TSL:2,
MTCH1-206 ENST00000492754.1 373 No protein Processed transcript - - - TSL:5,
Ubigene Red Cotton Transcript
Strategy Click to get
Red Cotton™ Assessment    
Project Difficulty Level unknown
Target Gene MTCH1
This KO Strategy loading
Red Cotton™ Notes Gene MTCH1 had been KO in hela cell line.
Aforementioned information comes from Ubigene database. Different origin of cell lines may have different condition. Ubigene reserved all the right for final explanation.
Special deals for this gene:


Single gRNA plasmid off-shelf


Single gRNA lentivirus

Work flow
Ubigene Red Cotton Workflow

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